We are interested in the pathogenic role of chronic inflammation in neoplastic transformation, for example the origins of liver cancer. Our researchers study the role of immune cells in the tumour microenvironment and anti-tumour immunity:
- what controls the balance between immune activation and tolerance towards tumours. How is this impacted by chronic infections and immune stimulants
- in innate cells what mechanisms contribute to or hinder anti-tumour immunity
- to what extent does immune dysregulation after checkpoint inhibitor therapy resemble spontaneous autoimmune disease
- how does the tumour microenvironment support tumour growth e.g. cutaneous T cell lymphoma and liver cancer
Contacts
